Lightener
Bl = [Blᵃ], [Blᵇ], and [Blᶜ]
ORIGINS
EFFICIENCY
> 88% inhibition of tyrosinase activity, an enzyme involved in melanin synthesis
> Inhibition of melanocyte differentiation and proliferation
In-Vivo :
> 273% increase in luminosity index after 28 days of application
> 10.1% increase in skin color index after 56 days of application (the higher the index, the lighter the skin)
> 12.58% reduction in the appearance of spots after 56 days of application
> 53% reduction in the amount of melanin contained in pigmentation spots after 56 days of application
ORIGINS
EFFICIENCY
> 35% decrease in tyrosinase activity (enzyme involved in melanin synthesis)
> 20% decrease in the expression of genes involved in the maturation of melanocytes
> Reduction in melanin formation, determined at the level of released and intracellular melanins.
In Vivo:
> 8% increase in skin lightening after 6 weeks, i.e. a whitening activity similar to hydroquinone (Hydroquinone: reference molecule for its whitening properties but can be irritating).
ORIGINS
EFFICIENCY
> 27% decrease in tyrosine synthesis (melanin precursor)
> 18% decrease in tyrosinase activity (enzyme involved in melanin synthesis)
> 17% decrease in the concentration of melanin in keratinocytes by reducing melanosome migration.
In-Vivo
> Color contrast between spots and adjacent skin decreased by 11% > Spots became lighter
> Spots lighten by 10% (measurement of melanin level)
> Adjacent skin areas lightened by 14% (melanin level measurement)
> 10% increase in lightening in the intensity of the spots
> 90% of women say their skin tone is lighter
> 85% of women say their skin tone is more even
> 85% of women report that their pigmentary imperfections have decreased
Serums containing this Nutri-Element™






